Troopers said the crash happened at 9:24 p.m. on Highway 52 just south of Morris.
The OHP report on the wreck states Harold Dorsey, Jr., 45, of Tulsa was heading south in a 2004 Acura RL 4-door car when he went left of center and struck a northbound 2013 Ford Explorer driven by Jacqueline Browning, 63, of Boynton.
The crash killed Dorsey, Browning and Browning's passenger, 64-year-old Jimmy Browning, according to the OHP.
The OHP says all three were wearing seat belts. Troopers said the cause of the collision remains under investigation.
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